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Identification of RNA polymerase III-transcribed Alu loci by computational screening of RNA-Seq data

Of the ∼1.3 million Alu elements in the human genome, only a tiny number are estimated to be active in transcription by RNA polymerase (Pol) III. Tracing the individual loci from which Alu transcripts originate is complicated by their highly repetitive nature. By exploiting RNA-Seq data sets and uni...

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Detalles Bibliográficos
Autores principales: Conti, Anastasia, Carnevali, Davide, Bollati, Valentina, Fustinoni, Silvia, Pellegrini, Matteo, Dieci, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333407/
https://www.ncbi.nlm.nih.gov/pubmed/25550429
http://dx.doi.org/10.1093/nar/gku1361