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NFATc2 mediates epigenetic modification of dendritic cell cytokine and chemokine responses to dectin-1 stimulation

The transcription factor NFATc2 regulates dendritic cell (DC) responses to microbial stimulation through the C-type lectin receptor dectin-1. But the genetic targets of NFATc2 and their effects on DC function remain largely unknown. Therefore we used ChIP-seq to conduct genome-wide mapping of NFATc2...

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Detalles Bibliográficos
Autores principales: Yu, Hong-Bing, Yurieva, Marina, Balachander, Akhila, Foo, Ivy, Leong, Xiangrong, Zelante, Teresa, Zolezzi, Francesca, Poidinger, Michael, Ricciardi-Castagnoli, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333412/
https://www.ncbi.nlm.nih.gov/pubmed/25550437
http://dx.doi.org/10.1093/nar/gku1369