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ACTN4 copy number increase as a predictive biomarker for chemoradiotherapy of locally advanced pancreatic cancer

BACKGROUND: Several clinical trials have compared chemotherapy alone and chemoradiotherapy (CRT) for locally advanced pancreatic cancer (LAPC) treatment. However, predictive biomarkers for optimal therapy of LAPC remain to be identified. We retrospectively estimated amplification of the ACTN4 gene t...

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Detalles Bibliográficos
Autores principales: Watanabe, T, Ueno, H, Watabe, Y, Hiraoka, N, Morizane, C, Itami, J, Okusaka, T, Miura, N, Kakizaki, T, Kakuya, T, Kamita, M, Tsuchida, A, Nagakawa, Y, Wilber, H, Yamada, T, Honda, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333489/
https://www.ncbi.nlm.nih.gov/pubmed/25602965
http://dx.doi.org/10.1038/bjc.2014.623