Cargando…

Non-canonical 3′-5′ Extension of RNA with Prebiotically Plausible Ribonucleoside 2′,3′-Cyclic Phosphates

[Image: see text] Ribonucleoside 2′,3′-cyclic phosphates (N>p’s) are generated by multiple prebiotically plausible processes and are credible building blocks for the assembly of early RNA oligomers. While N>p’s can be polymerized into short RNAs by non-enzymatic processes with variable efficie...

Descripción completa

Detalles Bibliográficos
Autores principales: Mutschler, Hannes, Holliger, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333585/
https://www.ncbi.nlm.nih.gov/pubmed/24660752
http://dx.doi.org/10.1021/ja4127714