Detection of Protein–Small Molecule Binding Using a Self-Referencing External Cavity Laser Biosensor

[Image: see text] High-throughput screening has enabled the identification of small molecule modulators of important drug targets via well-established colorimetric or fluorimetric activity assays. However, existing methods to identify small molecule binders of nonenzymatic protein targets lack eithe...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Peh, Jessie, Hergenrother, Paul J., Cunningham, Brian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333586/
https://www.ncbi.nlm.nih.gov/pubmed/24720510
http://dx.doi.org/10.1021/ja500636p

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333586/
https://www.ncbi.nlm.nih.gov/pubmed/24720510
http://dx.doi.org/10.1021/ja500636p

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