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Detection of Protein–Small Molecule Binding Using a Self-Referencing External Cavity Laser Biosensor
[Image: see text] High-throughput screening has enabled the identification of small molecule modulators of important drug targets via well-established colorimetric or fluorimetric activity assays. However, existing methods to identify small molecule binders of nonenzymatic protein targets lack eithe...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333586/ https://www.ncbi.nlm.nih.gov/pubmed/24720510 http://dx.doi.org/10.1021/ja500636p |