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In vitro acetylcholinesterase inhibition by psoralen using molecular docking and enzymatic studies

INTRODUCTION: Alzheimer's disease (AD) has increased at an alarming rate and is now a worldwide health problem. Inhibitors of acetylcholinesterase (AChE) leading to inhibition of acetylcholine breakdown constitute the main therapeutic strategy for AD. Psoralen was investigated as inhibitor of A...

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Detalles Bibliográficos
Autores principales: Somani, Gauresh, Kulkarni, Chinmay, Shinde, Prashant, Shelke, Rupesh, Laddha, Kirti, Sathaye, Sadhana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333625/
https://www.ncbi.nlm.nih.gov/pubmed/25709334
http://dx.doi.org/10.4103/0975-7406.148775