Cargando…

Mechanism of Ca(2+)-triggered ESCRT assembly and regulation of cell membrane repair

In muscle and other mechanically active tissue, cell membranes are constantly injured and their repair depends on the injury induced increase in cytosolic calcium. Here we show that injury-triggered Ca(2+) increase results in assembly of ESCRTIII and accessory proteins at the site of repair. This pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Scheffer, Luana L., Sreetama, Sen Chandra, Sharma, Nimisha, Medikayala, Sushma, Brown, Kristy J., Defour, Aurelia, Jaiswal, Jyoti K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333728/
https://www.ncbi.nlm.nih.gov/pubmed/25534348
http://dx.doi.org/10.1038/ncomms6646