Genetic targeting of NRXN2 in mice unveils role in excitatory cortical synapse function and social behaviors

Human genetics has identified rare copy number variations and deleterious mutations for all neurexin genes (NRXN1-3) in patients with neurodevelopmental diseases, and electrophysiological recordings in animal brains have shown that Nrxns are important for synaptic transmission. While several mouse m...

Descripción completa

Detalles Bibliográficos
Autores principales: Born, Gesche, Grayton, Hannah M., Langhorst, Hanna, Dudanova, Irina, Rohlmann, Astrid, Woodward, Benjamin W., Collier, David A., Fernandes, Cathy, Missler, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333794/
https://www.ncbi.nlm.nih.gov/pubmed/25745399
http://dx.doi.org/10.3389/fnsyn.2015.00003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333794/
https://www.ncbi.nlm.nih.gov/pubmed/25745399
http://dx.doi.org/10.3389/fnsyn.2015.00003

Ejemplares similares