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Mapping Splicing Quantitative Trait Loci in RNA-Seq

BACKGROUND: One of the major mechanisms of generating mRNA diversity is alternative splicing, a regulated process that allows for the flexibility of producing functionally different proteins from the same genomic sequences. This process is often altered in cancer cells to produce aberrant proteins t...

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Detalles Bibliográficos
Autores principales: Jia, Cheng, Hu, Yu, Liu, Yichuan, Li, Mingyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333812/
https://www.ncbi.nlm.nih.gov/pubmed/25733796
http://dx.doi.org/10.4137/CIN.S24832