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xCT, not just an amino-acid transporter: a multi-functional regulator of microbial infection and associated diseases

Expression of xCT, a component of the x(c)(–) amino-acid transporter, is essential for the uptake of cystine required for intracellular glutathione (GSH) synthesis and maintenance of the intracellular redox balance. Therefore, xCT plays an important role not only in the survival of somatic and immun...

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Detalles Bibliográficos
Autores principales: Dai, Lu, Noverr, Mairi C., Parsons, Chris, Kaleeba, Johnan A. R., Qin, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333839/
https://www.ncbi.nlm.nih.gov/pubmed/25745420
http://dx.doi.org/10.3389/fmicb.2015.00120