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Disruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancer
The Bcl proteins play a critical role in apoptosis, as mutations in family members interfere with normal programmed cell death. Such events can cause cell transformation, potentially leading to cancer. Recent discoveries indicate that some viral proteins interfere with Bcl proteins either directly o...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333878/ https://www.ncbi.nlm.nih.gov/pubmed/25699089 http://dx.doi.org/10.1186/1750-9378-9-44 |