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Disruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancer

The Bcl proteins play a critical role in apoptosis, as mutations in family members interfere with normal programmed cell death. Such events can cause cell transformation, potentially leading to cancer. Recent discoveries indicate that some viral proteins interfere with Bcl proteins either directly o...

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Detalles Bibliográficos
Autores principales: Alibek, Kenneth, Irving, Stephanie, Sautbayeva, Zarina, Kakpenova, Ainur, Bekmurzayeva, Aliya, Baiken, Yeldar, Imangali, Nurgul, Shaimerdenova, Madina, Mektepbayeva, Damel, Balabiyev, Arnat, Chinybayeva, Aizada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333878/
https://www.ncbi.nlm.nih.gov/pubmed/25699089
http://dx.doi.org/10.1186/1750-9378-9-44