Hoxa2 Selectively Enhances Meis Binding to Change a Branchial Arch Ground State

Hox transcription factors (TFs) are essential for vertebrate development, but how these evolutionary conserved proteins function in vivo remains unclear. Because Hox proteins have notoriously low binding specificity, they are believed to bind with cofactors, mainly homeodomain TFs Pbx and Meis, to s...

Descripción completa

Detalles Bibliográficos
Autores principales: Amin, Shilu, Donaldson, Ian J., Zannino, Denise A., Hensman, James, Rattray, Magnus, Losa, Marta, Spitz, François, Ladam, Franck, Sagerström, Charles, Bobola, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333904/
https://www.ncbi.nlm.nih.gov/pubmed/25640223
http://dx.doi.org/10.1016/j.devcel.2014.12.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333904/
https://www.ncbi.nlm.nih.gov/pubmed/25640223
http://dx.doi.org/10.1016/j.devcel.2014.12.024

Ejemplares similares