Expression of EGFR and Molecules Downstream to PI3K/Akt, Raf-1-MEK-1-MAP (Erk1/2), and JAK (STAT3) Pathways in Invasive Lung Adenocarcinomas Resected at a Single Institution

Therapies targeting EGFR are effective in treating tumors that harbor molecular alterations; however, there is heterogeneity in long-term response to these therapies. We retrospectively analyzed protein expression of EGFR, Stat3, phospho-Akt, and phospho-Erk1/2 by immunohistochemistry in a series of...

Descripción completa

Detalles Bibliográficos
Autores principales: Torres, Alba Fabiola, Nogueira, Cleto, Magalhaes, Juliana, Costa, Igor Santos, Aragao, Alessa, Neto, Antero Gomes, Martins, Filadelfia, Tavora, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334032/
https://www.ncbi.nlm.nih.gov/pubmed/25763322
http://dx.doi.org/10.1155/2014/352925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334032/
https://www.ncbi.nlm.nih.gov/pubmed/25763322
http://dx.doi.org/10.1155/2014/352925

Ejemplares similares