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The C-Type Lectin Receptor CLECSF8/CLEC4D Is a Key Component of Anti-Mycobacterial Immunity

The interaction of microbes with pattern recognition receptors (PRRs) is essential for protective immunity. While many PRRs that recognize mycobacteria have been identified, none is essentially required for host defense in vivo. Here, we have identified the C-type lectin receptor CLECSF8 (CLEC4D, MC...

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Detalles Bibliográficos
Autores principales: Wilson, Gillian J., Marakalala, Mohlopheni J., Hoving, Jennifer C., van Laarhoven, Arjan, Drummond, Rebecca A., Kerscher, Bernhard, Keeton, Roanne, van de Vosse, Esther, Ottenhoff, Tom H.M., Plantinga, Theo S., Alisjahbana, Bachti, Govender, Dhirendra, Besra, Gurdyal S., Netea, Mihai G., Reid, Delyth M., Willment, Janet A., Jacobs, Muazzam, Yamasaki, Sho, van Crevel, Reinout, Brown, Gordon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334100/
https://www.ncbi.nlm.nih.gov/pubmed/25674984
http://dx.doi.org/10.1016/j.chom.2015.01.004