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P2Y(2)R Deficiency Attenuates Experimental Autoimmune Uveitis Development

We aimed to study the role of the nucleotide receptor P2Y(2)R in the development of experimental autoimmune uveitis (EAU). EAU was induced in P2Y(2) (+/+) and P2Y(2) (-/-) mice by immunization with IRBP peptide or by adoptive transfer of in vitro restimulated semi-purified IRBP-specific enriched T l...

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Detalles Bibliográficos
Autores principales: Relvas, Lia Judice M., Makhoul, Maya, Dewispelaere, Remi, Caspers, Laure, Communi, Didier, Boeynaems, Jean-Marie, Robaye, Bernard, Bruyns, Catherine, Willermain, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334221/
https://www.ncbi.nlm.nih.gov/pubmed/25692550
http://dx.doi.org/10.1371/journal.pone.0116518