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Disulfide Bond Bridge Insertion Turns Hydrophobic Anticancer Prodrugs into Self-Assembled Nanomedicines

[Image: see text] It is commonly observed that hydrophobic molecules alone cannot self-assemble into stable nanoparticles, requiring amphiphilic or ionic materials to support nanoparticle stability and function in vivo. We report herein newly self-assembled nanomedicines through entirely different m...

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Detalles Bibliográficos
Autores principales: Wang, Yongjun, Liu, Dan, Zheng, Qingchuan, Zhao, Qiang, Zhang, Hongjuan, Ma, Yan, Fallon, John K., Fu, Qiang, Haynes, Matthew T., Lin, Guimei, Zhang, Rong, Wang, Dun, Yang, Xinggang, Zhao, Linxiang, He, Zhonggui, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334225/
https://www.ncbi.nlm.nih.gov/pubmed/25188744
http://dx.doi.org/10.1021/nl502044x