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Second Harmonic Super-resolution Microscopy for Quantification of mRNA at Single Copy Sensitivity

[Image: see text] Cell-specific information on the quantity and localization of key mRNAs at single copy sensitivity in single cells is critical for evaluating basic cellular process, disease risk, and efficacy of therapy. Quantification of overexpressed mRNAs beyond the diffraction limit is constra...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Cho, Il-Hoon, Cui, Yi, Irudayaraj, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334232/
https://www.ncbi.nlm.nih.gov/pubmed/25494326
http://dx.doi.org/10.1021/nn505096t