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Interactions of AsCy3 with Cysteine-Rich Peptides

[Image: see text] There is great interest in fluorogenic compounds that tag biomolecules within cells. Biarsenicals are fluorogenic compounds that become fluorescent upon binding four proximal Cys thiols, a tetracysteine (Cys(4)) motif. This work details interactions between the biarsenical AsCy3 an...

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Detalles Bibliográficos
Autores principales: Alexander, Seth C., Schepartz, Alanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334252/
https://www.ncbi.nlm.nih.gov/pubmed/24999741
http://dx.doi.org/10.1021/ol501721j