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Structure and Stereochemical Determination of Hypogeamicins from a Cave-Derived Actinomycete

[Image: see text] Culture extracts from the cave-derived actinomycete Nonomuraea specus were investigated, resulting in the discovery of a new S-bridged pyronaphthoquinone dimer and its monomeric progenitors designated hypogeamicins A–D (1–4). The structures were elucidated using NMR spectroscopy, a...

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Detalles Bibliográficos
Autores principales: Derewacz, Dagmara K., McNees, C. Ruth, Scalmani, Giovanni, Covington, Cody L., Shanmugam, Ganesh, Marnett, Lawrence J., Polavarapu, Prasad L., Bachmann, Brian O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334282/
https://www.ncbi.nlm.nih.gov/pubmed/25046128
http://dx.doi.org/10.1021/np400742p