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Improving intranasal delivery of neurological nanomedicine to the olfactory region using magnetophoretic guidance of microsphere carriers

BACKGROUND: Although direct nose-to-brain drug delivery has multiple advantages, its application is limited by the extremely low delivery efficiency (<1%) to the olfactory region where drugs can enter the brain. It is crucial to developing new methods that can deliver drug particles more effectiv...

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Detalles Bibliográficos
Autores principales: Xi, Jinxiang, Zhang, Ze, Si, Xiuhua A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334328/
https://www.ncbi.nlm.nih.gov/pubmed/25709443
http://dx.doi.org/10.2147/IJN.S77520