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Improving intranasal delivery of neurological nanomedicine to the olfactory region using magnetophoretic guidance of microsphere carriers
BACKGROUND: Although direct nose-to-brain drug delivery has multiple advantages, its application is limited by the extremely low delivery efficiency (<1%) to the olfactory region where drugs can enter the brain. It is crucial to developing new methods that can deliver drug particles more effectiv...
Autores principales: | Xi, Jinxiang, Zhang, Ze, Si, Xiuhua A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334328/ https://www.ncbi.nlm.nih.gov/pubmed/25709443 http://dx.doi.org/10.2147/IJN.S77520 |
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