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Expression and inactivation of glycogen synthase kinase 3 alpha/ beta and their association with the expression of cyclin D1 and p53 in oral squamous cell carcinoma progression

BACKGROUND: The study aims to evaluate the expression and activity of glycogen synthase kinase 3 isoforms α/β (GSK3α/β) and to assess their oncogenic potential through a correlation with the expression of cyclin D1 and p53 in oral cancer. METHODS: The expression of total and phosphorylated GSK3α/β a...

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Detalles Bibliográficos
Autores principales: Mishra, Rajakishore, Nagini, Siddavaram, Rana, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334357/
https://www.ncbi.nlm.nih.gov/pubmed/25645517
http://dx.doi.org/10.1186/s12943-015-0300-x