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CPEB mediated ZO-1 mRNA Localization is Required for Epithelial Tight Junction Assembly and Cell Polarity

CPEB is a translational regulatory sequence-specific RNA binding protein that controls germ cell development. Here we show that CPEB heterozygous female mice are fertile but contain disorganized mammary epithelial cells in which ZO-1 and claudin-3, apical tight junction proteins, are mis-localized....

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Detalles Bibliográficos
Autores principales: Nagaoka, Kentaro, Udagawa, Tsuyoshi, Richter, Joel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334452/
https://www.ncbi.nlm.nih.gov/pubmed/22334078
http://dx.doi.org/10.1038/ncomms1678