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Consistent Inhibition of Cyclooxygenase Drives Macrophages towards the Inflammatory Phenotype

Macrophages play important roles in defense against infection, as well as in homeostasis maintenance. Thus alterations of macrophage function can have unexpected pathological results. Cyclooxygenase (COX) inhibitors are widely used to relieve pain, but the effects of long-term usage on macrophage fu...

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Detalles Bibliográficos
Autores principales: Na, Yi Rang, Yoon, Yi Na, Son, Dain, Jung, Daun, Gu, Gyo Jeong, Seok, Seung Hyeok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334507/
https://www.ncbi.nlm.nih.gov/pubmed/25680189
http://dx.doi.org/10.1371/journal.pone.0118203