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Tribendimidine: Mode of Action and nAChR Subtype Selectivity in Ascaris and Oesophagostomum

The cholinergic class of anthelmintic drugs is used for the control of parasitic nematodes. One of this class of drugs, tribendimidine (a symmetrical diamidine derivative, of amidantel), was developed in China for use in humans in the mid-1980s. It has a broader-spectrum anthelmintic action against...

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Detalles Bibliográficos
Autores principales: Robertson, Alan P., Puttachary, Sreekanth, Buxton, Samuel K., Martin, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334517/
https://www.ncbi.nlm.nih.gov/pubmed/25679515
http://dx.doi.org/10.1371/journal.pntd.0003495