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Cholic Acid Induces a Cftr Dependent Biliary Secretion and Liver Growth Response in Mice

The cause of Cystic fibrosis liver disease (CFLD), is unknown. It is well recognized that hepatic exposure to hydrophobic bile salts is associated with the development of liver disease. For this reason, we hypothesize that, CFTR dependent variations, in the hepatic handling of hydrophobic bile salts...

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Detalles Bibliográficos
Autores principales: Bodewes, Frank A. J. A., Bijvelds, Marcel J., de Vries, Willemien, Baller, Juul F. W., Gouw, Annette S. H., de Jonge, Hugo R., Verkade, Henkjan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334531/
https://www.ncbi.nlm.nih.gov/pubmed/25680200
http://dx.doi.org/10.1371/journal.pone.0117599