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Quantitative survey of multiple CpGs from 5 genes identifies CpG methylation panel discriminating between high- and low-grade cervical intraepithelial neoplasia

BACKGROUND: Studies of methylation biomarkers for cervical cancer often involved only few randomly selected CpGs per candidate gene analyzed by methylation-specific PCR-based methods, with often inconsistent results from different laboratories. We evaluated the role of different CpGs from multiple g...

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Detalles Bibliográficos
Autores principales: Tian, Xiaoyi, Chen, Di, Zhang, Ran, Zhou, Jun, Peng, Xiaozhong, Yang, Xiaolin, Zhang, Xiuru, Zheng, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334603/
https://www.ncbi.nlm.nih.gov/pubmed/25699113
http://dx.doi.org/10.1186/s13148-014-0037-1