Cargando…

Newborn Hypoxia/Anoxia Inhibits Cardiomyocyte Proliferation and Decreases Cardiomyocyte Endowment in the Developing Heart: Role of Endothelin-1

In the developing heart, cardiomyocytes undergo terminal differentiation during a critical window around birth. Hypoxia is a major stress to preterm infants, yet its effect on the development and maturation of the heart remains unknown. We tested the hypothesis in a rat model that newborn anoxia acc...

Descripción completa

Detalles Bibliográficos
Autores principales: Paradis, Alexandra N., Gay, Maresha S., Wilson, Christopher G., Zhang, Lubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334650/
https://www.ncbi.nlm.nih.gov/pubmed/25692855
http://dx.doi.org/10.1371/journal.pone.0116600