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Kinetic characterization of lactate dehydrogenase in normal and malignant human breast tissues

BACKGROUND: Aerobic glycolysis rate is higher in breast cancer tissues than adjacent normal tissues which providethe ATP, lactate and anabolic precursors required for tumourgenesis and metastasis. Lactate dehydrogenase (LDH) is a critical enzyme during aerobic glycolysis as it is typically responsib...

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Detalles Bibliográficos
Autores principales: Talaiezadeh, Abdolhassan, Shahriari, Ali, Tabandeh, Mohammad Reza, Fathizadeh, Payam, Mansouri, Siavash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334850/
https://www.ncbi.nlm.nih.gov/pubmed/25705126
http://dx.doi.org/10.1186/s12935-015-0171-7