Antipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model

BACKGROUND: This study was designed to test a new approach to drug treatment of autism spectrum disorders (ASDs) in the Fragile X (Fmr1) knockout mouse model. METHODS: We used behavioral analysis, mass spectrometry, metabolomics, electron microscopy, and western analysis to test the hypothesis that...

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Detalles Bibliográficos
Autores principales: Naviaux, Jane C, Wang, Lin, Li, Kefeng, Bright, A Taylor, Alaynick, William A, Williams, Kenneth R, Powell, Susan B, Naviaux, Robert K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334917/
https://www.ncbi.nlm.nih.gov/pubmed/25705365
http://dx.doi.org/10.1186/2040-2392-6-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334917/
https://www.ncbi.nlm.nih.gov/pubmed/25705365
http://dx.doi.org/10.1186/2040-2392-6-1

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