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Design and Synthesis of Pyrazole-3-one Derivatives as Hypoglycaemic Agents
Pyrazole-3-one compounds were designed on the basis of docking studies of previously reported antidiabetic pyrazole compounds. The amino acid residues found during docking studies were used as guidelines for the modification of aromatic substitutions on pyrazole-3-one structure. Depending on the doc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334925/ https://www.ncbi.nlm.nih.gov/pubmed/25734015 http://dx.doi.org/10.1155/2015/670181 |