What can we learn from molecular dynamics simulations for GPCR drug design?

Recent years have seen a tremendous progress in the elucidation of experimental structural information for G-protein coupled receptors (GPCRs). Although for the vast majority of pharmaceutically relevant GPCRs structural information is still accessible only by homology models the steadily increasing...

Descripción completa

Detalles Bibliográficos
Autores principales: Tautermann, Christofer S., Seeliger, Daniel, Kriegl, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334948/
https://www.ncbi.nlm.nih.gov/pubmed/25709761
http://dx.doi.org/10.1016/j.csbj.2014.12.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334948/
https://www.ncbi.nlm.nih.gov/pubmed/25709761
http://dx.doi.org/10.1016/j.csbj.2014.12.002

Ejemplares similares