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A computational design approach for virtual screening of peptide interactions across K(+) channel families()
Ion channels represent a large family of membrane proteins with many being well established targets in pharmacotherapy. The ‘druggability’ of heteromeric channels comprised of different subunits remains obscure, due largely to a lack of channel-specific probes necessary to delineate their therapeuti...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334993/ https://www.ncbi.nlm.nih.gov/pubmed/25709757 http://dx.doi.org/10.1016/j.csbj.2014.11.004 |