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Accumulation of a Bioactive Benzoisochromanequinone Compound Kalafungin by a Wild Type Antitumor-Medermycin-Producing Streptomycete Strain

Medermycin and kalafungin, two antibacterial and antitumor antibiotics isolated from different streptomycetes, share an identical polyketide skeleton core. The present study reported the discovery of kalafungin in a medermycin-producing streptomycete strain for the first time. A mutant strain obtain...

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Detalles Bibliográficos
Autores principales: Lü, Jin, He, Qiang, Huang, Luyao, Cai, Xiaofeng, Guo, Wenwen, He, Jing, Zhang, Lili, Li, Aiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335000/
https://www.ncbi.nlm.nih.gov/pubmed/25695632
http://dx.doi.org/10.1371/journal.pone.0117690