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Accumulation of a Bioactive Benzoisochromanequinone Compound Kalafungin by a Wild Type Antitumor-Medermycin-Producing Streptomycete Strain
Medermycin and kalafungin, two antibacterial and antitumor antibiotics isolated from different streptomycetes, share an identical polyketide skeleton core. The present study reported the discovery of kalafungin in a medermycin-producing streptomycete strain for the first time. A mutant strain obtain...
Autores principales: | Lü, Jin, He, Qiang, Huang, Luyao, Cai, Xiaofeng, Guo, Wenwen, He, Jing, Zhang, Lili, Li, Aiying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335000/ https://www.ncbi.nlm.nih.gov/pubmed/25695632 http://dx.doi.org/10.1371/journal.pone.0117690 |
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