Exclusion of the Unfolded Protein Response in Light-Induced Retinal Degeneration in the Canine T4R RHO Model of Autosomal Dominant Retinitis Pigmentosa

PURPOSE: To examine the occurrence of endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) following acute light damage in the naturally-occurring canine model of RHO-adRP (T4R RHO dog). METHODS: The left eyes of T4R RHO dogs were briefly light-exposed and retinas collected 3, 6...

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Detalles Bibliográficos
Autores principales: Marsili, Stefania, Genini, Sem, Sudharsan, Raghavi, Gingrich, Jeremy, Aguirre, Gustavo D., Beltran, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335018/
https://www.ncbi.nlm.nih.gov/pubmed/25695253
http://dx.doi.org/10.1371/journal.pone.0115723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335018/
https://www.ncbi.nlm.nih.gov/pubmed/25695253
http://dx.doi.org/10.1371/journal.pone.0115723

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