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Tumor Cell Targeting by Iron Oxide Nanoparticles Is Dominated by Different Factors In Vitro versus In Vivo

Realizing the full potential of iron oxide nanoparticles (IONP) for cancer diagnosis and therapy requires selective tumor cell accumulation. Here, we report a systematic analysis of two key determinants for IONP homing to human breast cancers: (i) particle size and (ii) active vs passive targeting....

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Detalles Bibliográficos
Autores principales: NDong, Christian, Tate, Jennifer A., Kett, Warren C., Batra, Jaya, Demidenko, Eugene, Lewis, Lionel D., Hoopes, P. Jack, Gerngross, Tillman U., Griswold, Karl E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335054/
https://www.ncbi.nlm.nih.gov/pubmed/25695795
http://dx.doi.org/10.1371/journal.pone.0115636