Cargando…

Tumor Cell Targeting by Iron Oxide Nanoparticles Is Dominated by Different Factors In Vitro versus In Vivo

Realizing the full potential of iron oxide nanoparticles (IONP) for cancer diagnosis and therapy requires selective tumor cell accumulation. Here, we report a systematic analysis of two key determinants for IONP homing to human breast cancers: (i) particle size and (ii) active vs passive targeting....

Descripción completa

Detalles Bibliográficos
Autores principales:	NDong, Christian, Tate, Jennifer A., Kett, Warren C., Batra, Jaya, Demidenko, Eugene, Lewis, Lionel D., Hoopes, P. Jack, Gerngross, Tillman U., Griswold, Karl E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335054/ https://www.ncbi.nlm.nih.gov/pubmed/25695795 http://dx.doi.org/10.1371/journal.pone.0115636

Ejemplares similares

Antibody-mediated targeting of iron oxide nanoparticles to the folate receptor alpha increases tumor cell association in vitro and in vivo
por: Ndong, Christian, et al.
Publicado: (2015)

Connecting the sequence dots: shedding light on the genesis of antibodies reported to be designed in silico
por: Vásquez, Maximiliano, et al.
Publicado: (2019)

Iron dominated electromagnets: design, fabrication, assembly and measurements
por: Tanabe, Jack C
Publicado: (2005)

Functionalized superparamagnetic iron oxide nanoparticles provide highly efficient iron-labeling in macrophages for magnetic resonance–based detection in vivo
por: Sharkey, Jack, et al.
Publicado: (2017)

Advanced Statistics with Applications in R
por: Demidenko, Eugene
Publicado: (2019)

The p-Value You Can’t Buy
por: Demidenko, Eugene
Publicado: (2016)

Microarray enriched gene rank
por: Demidenko, Eugene
Publicado: (2015)

The next‐generation K‐means algorithm
por: Demidenko, Eugene
Publicado: (2018)

Impact of superparamagnetic iron oxide nanoparticles on in vitro and in vivo radiosensitisation of cancer cells
por: Russell, Emily, et al.
Publicado: (2021)

Monitoring the effects of dexamethasone treatment by MRI using in vivo iron oxide nanoparticle-labeled macrophages
por: Gramoun, Azza, et al.
Publicado: (2014)

Mixed models : theory and applications with R
por: Demidenko, Eugene, 1948-
Publicado: (2013)

In Vitro/In Vivo Toxicity Evaluation and Quantification of Iron Oxide Nanoparticles
por: Patil, Ujwal S., et al.
Publicado: (2015)

In Vivo MRI of Functionalized Iron Oxide Nanoparticles for Brain Inflammation
por: Tang, Tang, et al.
Publicado: (2018)

In vivo fate of free and encapsulated iron oxide nanoparticles after injection of labelled stem cells
por: Ashraf, Sumaira, et al.
Publicado: (2018)

Genomic evidence that microbial carbon degradation is dominated by iron redox metabolism in thawing permafrost
por: Romanowicz, Karl J., et al.
Publicado: (2023)

Metabolic pathway and distribution of superparamagnetic iron oxide nanoparticles: in vivo study
por: Schlachter, Eva K, et al.
Publicado: (2011)

Physical characterization and in vivo organ distribution of coated iron oxide nanoparticles
por: Sharma, Anirudh, et al.
Publicado: (2018)

In vivo Biodistribution and Clearance of Magnetic Iron Oxide Nanoparticles for Medical Applications
por: Nowak-Jary, Julia, et al.
Publicado: (2023)

Statistical determination of synergy based on Bliss definition of drugs independence
por: Demidenko, Eugene, et al.
Publicado: (2019)

Aerosolised micro and nanoparticle: formulation and delivery method for lung imaging
por: Munir, Miftakul, et al.
Publicado: (2022)

Computer-guided binding mode identification and affinity improvement of an LRR protein binder without structure determination
por: Choi, Yoonjoo, et al.
Publicado: (2020)

Investigation of magnetically controlled water intake behavior of Iron Oxide Impregnated Superparamagnetic Casein Nanoparticles (IOICNPs)
por: Singh, Anamika, et al.
Publicado: (2014)

E. coli Phagelysate: A Primer to Enhance Nanoparticles and Drug Deliveries in Tumor
por: Ghambashidze, Ketevan, et al.
Publicado: (2023)

Evaluation of Toxicity and Neural Uptake In Vitro and In Vivo of Superparamagnetic Iron Oxide Nanoparticles
por: Khalid, Muhammad Kamran, et al.
Publicado: (2018)

Biomarkers of oxidative stress for in vivo assessment of toxicological effects of iron oxide nanoparticles
por: Reddy, Utkarsh A., et al.
Publicado: (2017)

The In-Vivo Use of Superparamagnetic Iron Oxide Nanoparticles to Detect Inflammation Elicits a Cytokine Response but Does Not Aggravate Experimental Arthritis
por: Vermeij, Eline A., et al.
Publicado: (2015)

Development of polymeric–cationic peptide composite nanoparticles, a nanoparticle-in-nanoparticle system for controlled gene delivery
por: Jain, Arvind K, et al.
Publicado: (2015)

Particokinetics: computational analysis of the superparamagnetic iron oxide nanoparticles deposition process
por: Cárdenas, Walter HZ, et al.
Publicado: (2012)

Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer
por: Hampsch, Riley A., et al.
Publicado: (2017)

Basic design and engineering of normal-conducting, iron-dominated electromagnets
por: Zickler, Th.
Publicado: (2011)

Tremor-Dominant in Parkinson Disease: The Relevance to Iron Metabolism and Inflammation
por: Lian, Teng-Hong, et al.
Publicado: (2019)

Enhancement of Radiation Therapy through Blockade of the Immune Checkpoint, V-domain Ig Suppressor of T Cell Activation (VISTA), in Melanoma and Adenocarcinoma Murine Models
por: Duval, Kayla E. A., et al.
Publicado: (2023)

Anti-CEA-functionalized superparamagnetic iron oxide nanoparticles for examining colorectal tumors in vivo
por: Huang, Kai-Wen, et al.
Publicado: (2013)

Potential use of superparamagnetic iron oxide nanoparticles for in vitro and in vivo bioimaging of human myoblasts
por: Wierzbinski, Kamil R., et al.
Publicado: (2018)

MRI Study of the Influence of Surface Coating Aging on the In Vivo Biodistribution of Iron Oxide Nanoparticles
por: Carregal-Romero, Susana, et al.
Publicado: (2018)

In Vivo Assimilation of CuS, Iron Oxide and Iron Oxide@CuS Nanoparticles in Mice: A 6-Month Follow-Up Study
por: Curcio, Alberto, et al.
Publicado: (2022)

Chemically synthesized nanoparticles of iron and iron-carbides
por: Khurshid, Hafsa, et al.
Publicado: (2020)

Modification of the surface of superparamagnetic iron oxide nanoparticles to enable their safe application in humans
por: Strehl, Cindy, et al.
Publicado: (2016)

Protein Corona Composition of Superparamagnetic Iron Oxide Nanoparticles with Various Physico-Chemical Properties and Coatings
por: Sakulkhu, Usawadee, et al.
Publicado: (2014)

Surface Modification of Magnetic Iron Oxide Nanoparticles
por: Zhu, Nan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_otk3vbj8vav3m7he65m9i8h8p8