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Whole Cell Formaldehyde Cross-Linking Simplifies Purification of Mitochondrial Nucleoids and Associated Proteins Involved in Mitochondrial Gene Expression

Mitochondrial DNA/protein complexes (nucleoids) appear as discrete entities inside the mitochondrial network when observed by live-cell imaging and immunofluorescence. This somewhat trivial observation in recent years has spurred research towards isolation of these complexes and the identification o...

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Detalles Bibliográficos
Autores principales: Rajala, Nina, Hensen, Fenna, Wessels, Hans J. C. T., Ives, Daniel, Gloerich, Jolein, Spelbrink, Johannes N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335056/
https://www.ncbi.nlm.nih.gov/pubmed/25695250
http://dx.doi.org/10.1371/journal.pone.0116726