Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish

The genetic underpinnings of heart rate regulation are only poorly understood. In search for genetic regulators of cardiac pacemaker activity, we isolated in a large-scale mutagenesis screen the embryonic lethal, recessive zebrafish mutant schneckentempo (ste). Homozygous ste mutants exhibit a sever...

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Detalles Bibliográficos
Autores principales: Keßler, Mirjam, Berger, Ina M., Just, Steffen, Rottbauer, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335124/
https://www.ncbi.nlm.nih.gov/pubmed/25697682
http://dx.doi.org/10.1007/s00395-015-0468-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335124/
https://www.ncbi.nlm.nih.gov/pubmed/25697682
http://dx.doi.org/10.1007/s00395-015-0468-7

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