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Systems pharmacology approaches for optimization of antiangiogenic therapies: challenges and opportunities
Targeted therapies have become an important therapeutic paradigm for multiple malignancies. The rapid development of resistance to these therapies impedes the successful management of advanced cancer. Due to the redundancy in angiogenic signaling, alternative proangiogenic factors are activated upon...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335258/ https://www.ncbi.nlm.nih.gov/pubmed/25750626 http://dx.doi.org/10.3389/fphar.2015.00033 |