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Cas9 function and host genome sampling in Type II-A CRISPR–Cas adaptation

To acquire the ability to recognize and destroy virus and plasmid invaders, prokaryotic CRISPR–Cas systems capture fragments of DNA within the host CRISPR locus. Our results indicate that the process of adaptation by a Type II-A CRISPR–Cas system in Streptococcus thermophilus requires Cas1, Cas2, an...

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Detalles Bibliográficos
Autores principales: Wei, Yunzhou, Terns, Rebecca M., Terns, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335292/
https://www.ncbi.nlm.nih.gov/pubmed/25691466
http://dx.doi.org/10.1101/gad.257550.114