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Suppression of pervasive noncoding transcription in embryonic stem cells by esBAF

Approximately 75% of the human genome is transcribed, the majority of which does not encode protein. However, many noncoding RNAs (ncRNAs) are rapidly degraded after transcription, and relatively few have established functions, questioning the significance of this observation. Here we show that esBA...

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Detalles Bibliográficos
Autores principales: Hainer, Sarah J., Gu, Weifeng, Carone, Benjamin R., Landry, Benjamin D., Rando, Oliver J., Mello, Craig C., Fazzio, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335293/
https://www.ncbi.nlm.nih.gov/pubmed/25691467
http://dx.doi.org/10.1101/gad.253534.114