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A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages
The transcription factor (TF) interferon regulatory factor 8 (IRF8) controls both developmental and inflammatory stimulus-inducible genes in macrophages, but the mechanisms underlying these two different functions are largely unknown. One possibility is that these different roles are linked to the a...
Autores principales: | Mancino, Alessandra, Termanini, Alberto, Barozzi, Iros, Ghisletti, Serena, Ostuni, Renato, Prosperini, Elena, Ozato, Keiko, Natoli, Gioacchino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335295/ https://www.ncbi.nlm.nih.gov/pubmed/25637355 http://dx.doi.org/10.1101/gad.257592.114 |
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