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A high-sensitivity phospho-switch triggered by Cdk1 governs chromosome morphogenesis during cell division

The initiation of chromosome morphogenesis marks the beginning of mitosis in all eukaryotic cells. Although many effectors of chromatin compaction have been reported, the nature and design of the essential trigger for global chromosome assembly remain unknown. Here we reveal the identity of the core...

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Detalles Bibliográficos
Autores principales: Robellet, Xavier, Thattikota, Yogitha, Wang, Fang, Wee, Tse-Luen, Pascariu, Mirela, Shankar, Sahana, Bonneil, Éric, Brown, Claire M., D’Amours, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335297/
https://www.ncbi.nlm.nih.gov/pubmed/25691469
http://dx.doi.org/10.1101/gad.253294.114