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Escape from crossover interference increases with maternal age

Recombination plays a fundamental role in meiosis, ensuring the proper segregation of chromosomes and contributing to genetic diversity by generating novel combinations of alleles. Here, we use data derived from direct-to-consumer genetic testing to investigate patterns of recombination in over 4,20...

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Detalles Bibliográficos
Autores principales: Campbell, Christopher L., Furlotte, Nicholas A., Eriksson, Nick, Hinds, David, Auton, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335350/
https://www.ncbi.nlm.nih.gov/pubmed/25695863
http://dx.doi.org/10.1038/ncomms7260