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High MACC1 expression in combination with mutated KRAS G13 indicates poor survival of colorectal cancer patients

BACKGROUND: The metastasis-associated in colon cancer 1 (MACC1) gene has been identified as prognostic biomarker for colorectal cancer (CRC). Here, we aimed at the refinement of risk assessment by separate and combined survival analyses of MACC1 expression with any of the markers KRAS mutated in cod...

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Detalles Bibliográficos
Autores principales: Ilm, Katharina, Kemmner, Wolfgang, Osterland, Marc, Burock, Susen, Koch, Gudrun, Herrmann, Pia, Schlag, Peter M, Stein, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335361/
https://www.ncbi.nlm.nih.gov/pubmed/25742883
http://dx.doi.org/10.1186/s12943-015-0316-2