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Fruits and barks extracts of Zanthozyllum heitzii a spice from Cameroon induce mitochondrial dependent apoptosis and Go/G1 phase arrest in human leukemia HL-60 cells

BACKGROUND: Zanthoxylum heitzii is a spice used to prepare several dishes and to treat tumors, syphilis, malaria, cardiac palpitations, urogenital infections in the west region of Cameroon, but the antitumor mechanisms and chemical composition are not yet investigated. This study was aimed to determ...

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Detalles Bibliográficos
Autores principales: Pieme, Constant Anatole, Santosh, Guru Kumar, Tekwu, Emmanuel Mouafo, Askun, Tülin, Aydeniz, Hatice, Ngogang, Jeanne Yonkeu, Bhushan, Shashi, Saxena, Ajit Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335363/
https://www.ncbi.nlm.nih.gov/pubmed/25723957
http://dx.doi.org/10.1186/0717-6287-47-54