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HES5 silencing is an early and recurrent change in prostate tumourigenesis

Prostate cancer is the most common cancer in men, resulting in over 10 000 deaths/year in the UK. Sequencing and copy number analysis of primary tumours has revealed heterogeneity within tumours and an absence of recurrent founder mutations, consistent with non-genetic disease initiating events. Usi...

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Detalles Bibliográficos
Autores principales: Massie, Charles E, Spiteri, Inmaculada, Ross-Adams, Helen, Luxton, Hayley, Kay, Jonathan, Whitaker, Hayley C, Dunning, Mark J, Lamb, Alastair D, Ramos-Montoya, Antonio, Brewer, Daniel S, Cooper, Colin S, Eeles, Rosalind, Warren, Anne Y, Tavaré, Simon, Neal, David E, Lynch, Andy G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335379/
https://www.ncbi.nlm.nih.gov/pubmed/25560400
http://dx.doi.org/10.1530/ERC-14-0454